Description
The Neonatal Biotinidase Deficiency Screening ELISA is a quantitative enzyme immunoassay for detecting biotinidase enzyme deficiency in dried blood spots. It is designed for newborn screening and diagnostic laboratory use.
The kit is based on a catalysis reaction of biotinidase extracted from the sample. In the presence of an artificial substrate, biotinidase will release 4-aminobenzoic acid (PABA). The generated PABA will react with sodium nitrite to form a diazotized compound. The purple coloration obtained can be directly measured by absorption and is directly proportional to the biotinidase activity in the sample.
Format: 480 – 1920 determinations
Storage: At 2-8°C
Turn around time: Overnight test
The Neonatal Biotinidase Deficiency Screening ELISA is a quantitative enzyme immunoassay for detecting biotinidase enzyme deficiency in dried blood spots. It is designed for newborn screening and diagnostic laboratory use.
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