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Congenital Adrenal Hyperplasia (CAH) (colo)

The NEONATAL17-OHP Screening ELISA is a competitive ELISA in which both 17-OHP contained in the blood specimen and a labelled-17-OHP competitively bind to the anti-17-OHP antibodies covering the microplate. The labelled-17OHP is measured through the reduction of 3,3’-5,5’-tetramethylbenzidine (TMB) by the HRP. The intensity of this absorbance signal is therefore inversely proportional to the concentration of 17-OHP present in the newborn dried blood spot.

General information

Format: 192 – 576 – 1920 determinations
Storage: At 2-8°C
Possible automation: Yes
Turn around time: Less than 5 hours

SKU: 17OHP-002 Categories: ,
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Description

This immunoassay is used in diagnostic labs to detect elevated 17‑OHP, a biomarker for congenital adrenal hyperplasia (CAH), from newborn dried blood spot samples. The colorimetric protocol quantifies 17‑OHP levels via binding of an antibody and subsequent enzymatic color development.

The LaCAR immunoassay suite lists this among their neonatal screening assays, alongside TSH, IRT, PAP etc.

Further details—such as reagent stability, incubation times, calibration, and format options—are on the original product page.

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